![]() Vitamin K2 controls where that calcium ends up. Vitamin D controls the absorption of calcium into the blood. This analysis will focus on the interactions of D and K foremost. Vitamins A and D work together with bone health but help support the utilization of the other. Vitamin D and K2 work with one another to maintain tight control over calcium levels in the body. It’s even better if you consider Vitamin A supplementation too. If you’re taking Vitamin D, it is critical that you consider Vitamin K2 supplementation. Conclusions: The combination of vitamin K and D can significantly increase the total BMD and significantly decrease undercarboxylated osteocalcin, and a more favorable effect is expected when vitamin K 2 is used.Your Go-To Resource for D3 and K2 Supplementation Simultaneously, subgroup analysis showed that K 2 or vitamin K (not specified) supplement was less than 500 μg d −1, which when combined with vitamin D can significantly increase the total BMD compared with the control group fed a normal diet or the group with no treatment (0.479, 0.101 to 0.858 and 0.570, 0.196 to 0.945). A significant decrease in undercarboxylated osteocalcin (−0.945, −1.113 to −0.778) can be observed with the combination of vitamin K and D. ![]() Vitamin K combined with vitamin D significantly increased the total bone mineral density (BMD): the pooled effect size was 0.316. Method and findings: A comprehensive search on Web of Science, PubMed, Embase and the Cochrane Library (from 1950 to February 2020) and bibliographies of relevant articles was undertaken, with the meta-analysis of eight randomized controlled trials (RCTs) including a total of 971 subjects. ![]() Background: Previous studies did not draw a consistent conclusion about the effects of vitamin K combined with vitamin D on human skeletal quality. ![]()
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